Pathological Conditions Occurring in the Thymus as a Result of Exposure to Heavy Metals Such as Chromium, Mercury, Arsenic, And Nickel
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Keywords

thymus
heavy metals
chromium
arsenic
nikel
mercury
apoptosis
thymic involution
atrophy
autoimmune diseases

How to Cite

Khusniddin qizi, K. S. ., & Ravshan qizi, K. F. . (2025). Pathological Conditions Occurring in the Thymus as a Result of Exposure to Heavy Metals Such as Chromium, Mercury, Arsenic, And Nickel. Spanish Journal of Innovation and Integrity, 41, 31–36. Retrieved from https://www.sjii.es/index.php/journal/article/view/394

Abstract

This article provides a comprehensive analysis based on scientific research, experimental models, and clinical observations of the impact of heavy metals distributed in the environment of industrialized societies on the human body, particularly on the thymus — the central organ of the immune system. According to the research results, chromium, mercury, arsenic, nikel, and other heavy metals cause oxidative stress, inflammation, apoptosis, and epigenetic changes in cells.Moreover, gene regulation disorders, signal transduction disruption, and cellular mechanism dysfunction lead to immunosuppression, decreased protection against infections, and the development of autoimmune conditions.

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