Abstract
In addition to various microorganisms that enter the body from the external environment, there are also microorganisms that live in symbiosis with the human body and make up the normal human microflora. They are located in different biotopes and are important for the functioning of the body. One of these biotopes is the large intestine, the standard microflora of which, consisting of indigenous and facultative microorganisms, is of great importance for life. It is known that the microbiocenosis of the large intestine consists of more than 450 microorganisms and participates in the metabolism of the "host" of the body and the formation of colonization resistance in the intestine.